Aerobic exercise and weight reduction are two of the strongest lifestyle tools By David Dunaief, M.D. Osteoarthritis (OA) is more than an annoyance. It affects your mobility, mood, and sleep quality, all of which can reduce your quality of life. While OA can affect any joints, it affects the knees, hips and hands most often. Acetaminophen and nonsteroidal anti-inflammatory drugs, such as ibuprofen or naproxen, might relieve your immediate symptoms; however, they don’t slow osteoarthritis’ progre