technology
Tumors Can Hide p53 Neoantigens from T Cells, Study Finds

Researchers reveal how tumors suppress p53 neoantigen presentation and that targeting ERAP1 can restore T-cell recognition of cancer cells.
Mutations in the tumor suppressor TP53 are among the most common genetic alterations in cancer, making mutant p53 an attractive target for personalized immunotherapies. However, new research suggests that identifying a tumor mutation may be only the ... [3434 chars]
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