health
What SIRPα reveals about how breast cancer takes hold in the brain
Scientists at Wake Forest University School of Medicine have uncovered a previously unrecognised cancer-intrinsic role for SIRPα in triple-negative breast cancer, linking the cell-surface protein to mitochondrial fission, tumour-cell migration and suppression of the brain’s immune defences.
Scientists at Wake Forest University School of Medicine have identified a previously underappreciated role for SIRPα in triple-negative breast cancer (TNBC), suggesting the protein could help cancer cells survive the journey to the brain and establis... [4803 chars]
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