Rapid Response to Fu et al.: Starting Right, But How Far Right?

Agreement: I Agree Body: Dear Editor Fu et al. provide a valuable and timely contribution to the target trial emulation literature, offering clear procedural guidance for aligning eligibility (E), treatment assignment (A), and time zero (T0) in observational studies. Their decision diagram is a practical tool that will help investigators avoid common design errors. We offer a complementary perspective that extends their framework in two important respects. First, Fu et al.'s three trial types ca